Manny Ramirez is not the problem. Note that absent Manny, David Ortiz didn't see anything to hit and his production will fall.
The issue is additional pitching staff stability, although Bradford seems to have helped. It would be great to get more for the top of the rotation, which would clearly require trading something of value, and at this point Bill Mueller has looked pretty sharp lately, too.
If the Sox are just trying to dump Manny, that's hardly a viable strategy to build a better team.